道医门大弟子陈道清与师妹文娇娇联手对抗九医门尹之平，揭露其用圣水传播尸毒控制民众的阴谋。尹之平勾结九菊门多次暗算，陈道清凭借玄天灵体反制毒素，最终并夺回被盗的《太上医典》
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全70集草根女歌手沈寒，三年前因为从火场中救下男友楚宇，受伤导致双目失明，又被大哥沈南星，二哥沈南城安排，做歌手苏曼的替唱，苏曼答应沈寒会帮她出道，可是苏曼成为天后那天食言了，沈寒站出来指控苏曼假唱，却被男友和亲哥哥打晕，而后不幸离世。重生后的沈寒决心不再被人利用，复明后，瞒着所有人，在苏曼的演唱会上，揭穿了她假唱的黑幕，并展示了自己的才华，被影商歌三界大佬看中，以高价签约，从此步入天王行列！
全61集为了对抗包办婚姻，傅亭舟连妻子乔南意面都没见一次，便抛下她带着“好兄弟”萧雨桐出国，直到两年后才回来，然而他以为的无趣妻子，其实是个古代花魁，上一世凭着过人的心机和美貌成了高门主母，更是没将他的冷落放在心里。只不过区区两年，乔南意就收服了傅家所有人的心。这时候傅亭舟突然回来，还带着萧雨桐等朋友们，在朋友们故意调侃讽刺乔南意是个古板无盐女时，乔南意突然露面，让所有人惊艳不已，傅亭舟更是一见钟情，这让本就觊觎傅亭舟的萧雨桐嫉恨不已，便故意激将乔南意参加朋友聚会，想让她看自己和傅亭舟在酒吧舞台上情歌对唱，好羞辱
9.0全69集秦浩之子秦小阳在励志中心离奇死亡，秦浩被冤判死刑。重生后他仍未能阻止悲剧，调查发现是励志中心伪造证据。开棺验尸牵出“活埋双胞胎长子”陋习，秦汉、王晓梅合谋复仇，最终二人获刑，秦浩夫妇呼吁破除迷信。
10.0全28集母亲知道儿子即将被爷爷拉去手术换皮，儿子这辈子将变得生不如死，她非但没有阻止，还嘱咐医生一定要执行手术，只因为上一世她成功阻止儿子落得这个下场，但是儿子却一直记恨她...
8.0全100集魏胜蓝是杂志项目经理，温文尔雅。陆青青是设计新人，因帮杨汤缓解头痛被魏母刘若雅误解。李芳华为让女儿变好，带她见礼仪大师。陆青青在成长中与门波互生情愫，还调解同事矛盾、助团队团结。魏胜蓝认可她后鼓励其参加比赛，陆青青获奖，刘若雅得知真相与李芳华和好。
全80集林茉一睁眼发现自己穿越到了死后第十一年。弥留之际她得知这个世界是一本小说，三个弟弟都是原书男女主的对照组反派，下场凄惨，林茉难以接受自己可爱的弟弟和自己成为男女主play的一环，于是果断出手，斩断孽缘，却毫无察觉自己曾经的死对头在再次见到自己的那一刻，迷恋痴迷的目光。
8.0全70集程漠遭继母周慧姬算计，被父抽髓救弟、逐出家们，母被害。多年后以“暗夜君王”回归，与温见月订婚却遭嫌弃。他隐忍布局，揭赵方雄诬陷、周慧姬毒母真相，杀仇人。化解程野炸弹，救中毒的温见月，求婚成功，赢回尊严与真爱。
全90集贺京准奶奶用计将江宝瓷送到其身边，江宝瓷为生活费追贺京准一年多。结婚后江宝瓷受委屈仍为贺京准谋贺家主权，身心俱疲。她离开时贺京准挽留，后因谋杀、大火婚姻濒危，贺京准醒悟追妻。
10.0全79集实习医生夏天被女友抛弃后觉醒 “超级神医系统”，获顶级医术。他在医院救死扶伤，从处理急诊到完成高难度手术，渐成明星医生，前女友则因贪慕虚荣自食恶果。